{"id":69,"date":"2020-01-27T08:05:29","date_gmt":"2020-01-27T08:05:29","guid":{"rendered":"https:\/\/demosites.io\/web-agency-gb\/?page_id=69"},"modified":"2026-01-18T16:31:28","modified_gmt":"2026-01-18T16:31:28","slug":"15c42-web-agency-gb-research","status":"publish","type":"page","link":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/","title":{"rendered":"Research"},"content":{"rendered":"\n
<\/span>
\n
\n

Research<\/h1>\n<\/div><\/div>\n\n\n\n

All NBLab publications
<\/a>GoogleScholar profile<\/a><\/p>\n<\/div><\/div>\n\n\n\n

<\/span>
\n
\n
<\/div>\n\n\n\n
\n
\n
\"\"<\/figure>\n\n\n\n

Cellular mechanisms of learning and memory processes during postnatal development<\/h3>\n\n\n\n

NBLab recent studies have shown that long-term plasticity processes are involved in working memory and recency memory functions.<\/p>\n\n\n\n

\n
PROJECT DETAILS<\/a><\/div>\n<\/div>\n\n\n\n
<\/div>\n<\/div>\n\n\n\n
\n
\"\"<\/figure>\n\n\n\n

Adaptations in brain disorders and investigation of possible treatments<\/h3>\n\n\n\n

The prefrontal cortex is a brain area that continues to develop until adulthood. We still lack significant knowledge abou the developmental events that take place in the prefrontal cortex from birth to adulthood. Several neurodevelopmental disorders, such as schizophrenia, emerge as a result of defects during early development, which manifest in adolescence or adulthood. Understanding the early life adaptations will lead to development of better diagnostic tools and more effective treatments.<\/p>\n\n\n\n

\n
PROJECT DETAILS<\/a><\/div>\n<\/div>\n\n\n\n
<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n
\n
<\/div>\n\n\n\n
<\/div>\n<\/div>\n\n\n\n
\n
\n

Investigation of novel therapeutic approaches for Alzheimer’s disease<\/h3>\n\n\n\n

Current projects:<\/p>\n\n\n\n

    \n
  1. Can cannabidiol and derivatives of cannabidiol reverse the cognitive deficits in the 5XFAD animal model of Alzheimer’s disease?<\/li>\n\n\n\n
  2. Can we use scaffolds carrying either drugs or cells to reverse cognitive deficits in Alzheimer’s disease? (in collaboration with Dimitris Tzeranis and Ioannis Charalampopoulos)<\/li>\n\n\n\n
  3. Investigation of the potential of olive oil constituents to impove cognitive deficits in Alzheimer’s disease. <\/li>\n<\/ol>\n<\/div>\n\n\n\n
    \n

    Investigation of novel therapeutic compounds for epilepsy<\/h3>\n\n\n\n

    Current projects:<\/p>\n\n\n\n

      \n
    1. Investigation of cannabidiol and GIRK activators on epileptic activity<\/li>\n\n\n\n
    2. Investigation of cannabis and olive oil constituents on epileptic activity<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n
      <\/span>
      \n
      \n
      <\/div>\n\n\n\n
      \n
      \n
      \"\"<\/figure>\n\n\n\n

      Behavioral techniques<\/h3>\n\n\n\n

      We use several behavioral tasks to study anxiety, learning and memory processes and social behavior.\u00a0<\/p>\n\n\n\n

      \n
      PROJECT DETAILS<\/a><\/div>\n<\/div>\n<\/div>\n\n\n\n
      \n
      \"\"<\/figure>\n\n\n\n

      Electrophysiological techniques<\/h3>\n\n\n\n

      We use the brain slice preparation for spontaneous and evoked field potential recordings and for patch-clamp recordings.<\/p>\n\n\n\n

      \n
      PROJECT DETAILS<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n
      <\/span>
      \n
      <\/div>\n\n\n\n\n\n
      <\/div>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"neve_meta_sidebar":"full-width","neve_meta_container":"","neve_meta_enable_content_width":"on","neve_meta_content_width":100,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"on","footnotes":""},"class_list":["post-69","page","type-page","status-publish","hentry"],"yoast_head":"\nResearch - Neurophysiology and Behavior Lab<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research - Neurophysiology and Behavior Lab\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/\" \/>\n<meta property=\"og:site_name\" content=\"Neurophysiology and Behavior Lab\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/profile.php?id=100063801632416\" \/>\n<meta property=\"article:modified_time\" content=\"2026-01-18T16:31:28+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2020\/01\/neve-web-design-bg-10.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"600\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@swimgr2\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/\",\"url\":\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/\",\"name\":\"Research - Neurophysiology and Behavior Lab\",\"isPartOf\":{\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/mechanisms-memory-284x300.png\",\"datePublished\":\"2020-01-27T08:05:29+00:00\",\"dateModified\":\"2026-01-18T16:31:28+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#primaryimage\",\"url\":\"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/mechanisms-memory.png\",\"contentUrl\":\"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/mechanisms-memory.png\",\"width\":1397,\"height\":1477},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.sidiropouloulab.com\/home\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/#website\",\"url\":\"https:\/\/www.sidiropouloulab.com\/home\/\",\"name\":\"Neurophysiology and Behavior Lab\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.sidiropouloulab.com\/home\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/#organization\",\"name\":\"Neurophysiology and Behavior Lab\",\"url\":\"https:\/\/www.sidiropouloulab.com\/home\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/NBLab-logo.png\",\"contentUrl\":\"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/NBLab-logo.png\",\"width\":1716,\"height\":1988,\"caption\":\"Neurophysiology and Behavior Lab\"},\"image\":{\"@id\":\"https:\/\/www.sidiropouloulab.com\/home\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/profile.php?id=100063801632416\",\"https:\/\/x.com\/swimgr2\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Research - Neurophysiology and Behavior Lab","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/","og_locale":"en_US","og_type":"article","og_title":"Research - Neurophysiology and Behavior Lab","og_url":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/","og_site_name":"Neurophysiology and Behavior Lab","article_publisher":"https:\/\/www.facebook.com\/profile.php?id=100063801632416","article_modified_time":"2026-01-18T16:31:28+00:00","og_image":[{"width":600,"height":600,"url":"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2020\/01\/neve-web-design-bg-10.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_site":"@swimgr2","twitter_misc":{"Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/","url":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/","name":"Research - Neurophysiology and Behavior Lab","isPartOf":{"@id":"https:\/\/www.sidiropouloulab.com\/home\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#primaryimage"},"image":{"@id":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#primaryimage"},"thumbnailUrl":"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/mechanisms-memory-284x300.png","datePublished":"2020-01-27T08:05:29+00:00","dateModified":"2026-01-18T16:31:28+00:00","breadcrumb":{"@id":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#primaryimage","url":"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/mechanisms-memory.png","contentUrl":"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/mechanisms-memory.png","width":1397,"height":1477},{"@type":"BreadcrumbList","@id":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/15c42-web-agency-gb-research\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.sidiropouloulab.com\/home\/"},{"@type":"ListItem","position":2,"name":"Research"}]},{"@type":"WebSite","@id":"https:\/\/www.sidiropouloulab.com\/home\/#website","url":"https:\/\/www.sidiropouloulab.com\/home\/","name":"Neurophysiology and Behavior Lab","description":"","publisher":{"@id":"https:\/\/www.sidiropouloulab.com\/home\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.sidiropouloulab.com\/home\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.sidiropouloulab.com\/home\/#organization","name":"Neurophysiology and Behavior Lab","url":"https:\/\/www.sidiropouloulab.com\/home\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.sidiropouloulab.com\/home\/#\/schema\/logo\/image\/","url":"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/NBLab-logo.png","contentUrl":"https:\/\/www.sidiropouloulab.com\/home\/wp-content\/uploads\/2022\/08\/NBLab-logo.png","width":1716,"height":1988,"caption":"Neurophysiology and Behavior Lab"},"image":{"@id":"https:\/\/www.sidiropouloulab.com\/home\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/profile.php?id=100063801632416","https:\/\/x.com\/swimgr2"]}]}},"_links":{"self":[{"href":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/wp-json\/wp\/v2\/pages\/69","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/wp-json\/wp\/v2\/comments?post=69"}],"version-history":[{"count":11,"href":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/wp-json\/wp\/v2\/pages\/69\/revisions"}],"predecessor-version":[{"id":867,"href":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/wp-json\/wp\/v2\/pages\/69\/revisions\/867"}],"wp:attachment":[{"href":"https:\/\/www.sidiropouloulab.com\/home\/index.php\/wp-json\/wp\/v2\/media?parent=69"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}